La Grande Crème
La Grande Crème

La Grande Crème

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Epigenetic discoveries show that it is now possible to repair negative traits within cells and counter cutaneous aging.


For the very first time, Biologique Recherche has identified and selected EpigenActiv©, a peptide that acts on EGF (or epidermal growth factor) receptors, which are essential to regenerate tissues and recycle degraded proteins. It acts on the cutaneous aging process to promote genuine cellular regeneration.

This discovery gave rise to La Grande Crème.

La Grande Crème is Biologique Recherche’s new innovation for skin affected by cutaneous aging. It promotes regeneration to renew strength and epidermal restructuring. This revolutionary cream tackles all age-related phenomena, for a facial treatment that is both complete and effective.

• Regenerating: genuine cellular revival
• Structuring and volumizing: provides a lifting effect
• Firming: improves the skin’s biomechanical properties
• Anti-wrinkle: diminishes the size and depth of wrinkles
• Anti-spot: diminishes pigmentation irregularities
• Protective: improves the quality of the skin barrier